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TruthBook Religious News Blog



Friday, August 07, 2009

God on the brain at Penn’s Neuroscience Boot Camp

August 5th, 2009
Tom Heneghan

Neurotheology - the study of the link between belief and the brain - is a topic I’ve hesitated to write about for several years. There are all kinds of theories out there about how progress in neuroscience is changing our understanding of religion, spirituality and mystical experience. Some say the research proves religion is a natural product of the way the brain works, others that God made the brain that way to help us believe. I knew so little about the science behind these ideas that I felt I had to learn more about the brain first before I could comment.

If that was an excuse for procrastination, I don’t have it anymore. For all this week and half the next, I’m attending a "Neuroscience Boot Camp" at the University of Pennsylvania in Philadelphia. This innovative program, run by Penn’s Center for Cognitive Neuroscience Director Martha Farah (photo below), aims to explain the latest research in neuroscience to 34 non-experts from fields such as law, business, philosophy and religious studies (as well as to a few journalists). The focus is not only on religion, but faith and issues related to it are certainly part of the discussion.

After only two of 8-1/2 days of lectures, one takeaway message is already clear. You can forget about the "God spot" that headline writers love to highlight (as in "'God spot' is found in Brain" or "Scientists Locate 'God Spot' in Human Brain"). There is no one place in the brain responsible for religion, just as there is no single location in the brain for love or language or identity. Most popular articles these days actually say that, but the headline writers continue to speak of a single spot.

"There isn’t a separate religious area of the brain, from what we can tell from the data," said Dr. Andrew Newberg, an associate professor of radiology and psychiatry at the Penn university hospital and author of several books on neuroscience and religion. "It’s not like there’s a little spiritual spot that lights up every time somebody thinks of God. When you look at religious and spiritual experiences, they are incredibly rich and diverse. Sometimes people find them on the emotional level, sometimes on an ideological level, sometimes they perceive a oneness, sometimes they perceive a person. It depends a lot on what the actual experience is."

Please click on "external source" for the complete article.

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Friday, June 19, 2009

Brain waves or beatific vision?

Tue, Jun. 16, 2009

Mystical experiences under the microscope
By David O'Reilly

Inquirer Staff Writer

As mystical experiences go, Barbara Bradley Hagerty's transcendent moment was not the kind that launches a new world religion. Still, it changed her forever.

The day was June 10, 1995. Hagerty, religion reporter for National Public Radio, was interviewing a terminally ill melanoma patient, Kathy, whose sunny outlook and trust in Jesus seemed to have prolonged her life, inexplicably, for years.

Then, as they talked, "I felt the hair on the back of my neck stand on end," Hagerty writes in her new book, Fingerprints of God, a survey of modern scientific investigation into religious experience.

"The air grew warmer and heavier, as if someone had moved into the circle [of lamplight] and was breathing on us. I glanced at Kathy." She, too, felt something and had "fallen silent in mid-sentence."

"I felt an unseen caress, engulfed by a presence I could feel but not touch," Hagerty continues. "I was paralyzed. . . . After a minute, although it seemed longer, the presence melted away."

What was it she sensed? Jesus? An angelic being? Or, as one researcher later suggested, had the temporal lobe of her brain been briefly hyperstimulated? This, he told her, likely induced the illusion of an unseen presence.

Whatever it was, it proved the "continental divide in my life," Hagerty said during a recent interview. "I decided I should investigate, the way we journalists do."

Her investigation grew into Fingerprints of God, a lucid overview of an essential question: Is mystical experience truly a glimpse of the divine, the eternal, the absolute? Or are the seemingly transformative moments known variously as "enlightenment" or "beatific vision" or cosmic bliss merely swells and quells in brain activity, signifying nothing beyond ourselves?

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Monday, April 27, 2009

RD10Q: Thinking About God Makes Your Brain Bigger

RD10Q: Thinking About God Makes Your Brain Bigger
By Andrew Newberg and Mark Robert Waldman
April 24, 2009

A new book argues that spiritual practices, be they secular or religious, are inherently good for you. Meditation and prayer—be it about God, or evolution, or peace, or the Big Bang—will actually change your brain.

Ten Questions for Andrew Newberg and Mark Waldman on How God Changes Your Brain, (Ballantine, 2009).

What inspired the two of you to write How God Changes Your Brain? What sparked your interest?

Our newest brain-scan research showed that different forms of meditation and spiritual practice can actually improve memory, and it may even slow down the aging process itself. We had also gathered enough data to draw a more comprehensive picture of how spiritual practices affect and change different parts of the brain, and we wanted to share this new perspective with the general public. We also wanted to present evidence showing how the religious landscape of America is moving from traditional values to a more spiritual and science-based vision of the universe.

What’s the most important take-home message for readers?

Spiritual practices, secular or religious, are inherently good for your body, and especially your brain. Meditation and prayer—be it about God, or evolution, or peace, or the Big Bang—will strengthen important circuits in your brain, making you more socially aware and alert while reducing anxiety, depression, and neurological stress. And meditation can be adapted in endless ways. You can use it to become more motivated to succeed in business. You can apply it to communication to reduce relationship conflicts. You can do a sixty-second meditation involving yawning to quickly relax your body and mind. Indeed, you can use the same technique to bring a roomful of children, students, or CEOs to attention with their brains becoming acutely attuned to each other: a fancy way of saying that yawning can actually evoke social empathy with many living species on this planet.

Please click on "external source" to access the entire interview with the authors.

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Wednesday, March 11, 2009

Religious Thoughts and Feelings Not Limited to One Part of Brain

By NICHOLAS WADE
Published: March 9, 2009

Brain researchers trying to understand the neural basis of religious belief have concluded that the brain has no special region or network for this task. Rather, it depends on general networks that exist for other purposes.

A team led by Dr. Jordan Grafman of the National Institute of Neurological Disorders and Stroke questioned volunteers about their religious beliefs while monitoring the blood flow in their brains with a scanning machine. Extra blood flow is assumed to reflect the activity of neurons in a specific region of the brain.

Different networks of neurons sprang into action when subjects were asked their view of three sets of statements about the religious beliefs, Dr. Grafman and colleagues report in this week’s Proceedings of the National Academy of Sciences.

In all three cases the neural activity in the subjects’ brains corresponded to brain networks known to have other, nonreligious functions. These include the theory of mind networks, used to predict other people’s intentions.

Dr. Andrew Newberg, director of the Center for Spirituality and the Mind at the University of Pennsylvania, said Dr. Grafman’s findings were in line with other research that has so far failed to find any specific structure in the brain that is dedicated to religious belief. “Religion has so many different aspects that it would be very unlikely to find one spot in the brain where religion and God reside,” Dr. Newberg said.

But he expressed doubt as to whether the biological correlates of religious belief, as visualized in brain scans like those taken by Dr. Grafman, in fact captured all of what religion is. “There may be other elements that science is not capable of measuring,” Dr. Newberg said.

In his own work Dr. Newberg looks at subjects undergoing religious experiences, like speaking in tongues or meditating. In “How God Changes Your Brain,” a book being published later this month, Dr. Newberg reports that certain regions of subjects’ brains have enlarged areas of neural activation after many months of intensive meditation.

He questioned whether asking subjects questions about religion when they were not in a religious frame of mind would capture much of interest about religious belief.

Dr. Grafman said that religious cohesion for a common purpose, and the ability to infer what others are thinking, would each have been favored by evolution, along with the theory of mind networks that serves both systems.

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Tuesday, February 17, 2009

The Biology of Belief

The Biology of Belief
By JEFFREY KLUGER Thursday, Feb. 12, 2009

This is page one of a four-page article - well worth the read. Please click on "external source" to access the entire article

Most folks probably couldn't locate their parietal lobe with a map and a compass. For the record, it's at the top of your head — aft of the frontal lobe, fore of the occipital lobe, north of the temporal lobe. What makes the parietal lobe special is not where it lives but what it does — particularly concerning matters of faith.

If you've ever prayed so hard that you've lost all sense of a larger world outside yourself, that's your parietal lobe at work. If you've ever meditated so deeply that you'd swear the very boundaries of your body had dissolved, that's your parietal too. There are other regions responsible for making your brain the spiritual amusement park it can be: your thalamus plays a role, as do your frontal lobes. But it's your parietal lobe — a central mass of tissue that processes sensory input — that may have the most transporting effect. (Read "Top 10 Medical Breakthroughs".)

Needy creatures that we are, we put the brain's spiritual centers to use all the time. We pray for peace; we meditate for serenity; we chant for wealth. We travel to Lourdes in search of a miracle; we go to Mecca to show our devotion; we eat hallucinogenic mushrooms to attain transcendent vision and gather in church basements to achieve its sober opposite. But there is nothing we pray — or chant or meditate — for more than health.

Health, by definition, is the sine qua non of everything else. If you're dead, serenity is academic. So we convince ourselves that while our medicine is strong and our doctors are wise, our prayers may heal us too.

Here's what's surprising: a growing body of scientific evidence suggests that faith may indeed bring us health. People who attend religious services do have a lower risk of dying in any one year than people who don't attend. People who believe in a loving God fare better after a diagnosis of illness than people who believe in a punitive God. No less a killer than AIDS will back off at least a bit when it's hit with a double-barreled blast of belief. "Even accounting for medications," says Dr. Gail Ironson, a professor of psychiatry and psychology at the University of Miami who studies HIV and religious belief, "spirituality predicts for better disease control." (Read "Finding God on YouTube.")

It's hard not to be impressed by findings like that, but a skeptic will say there's nothing remarkable — much less spiritual — about them. You live longer if you go to church because you're there for the cholesterol-screening drive and the visiting-nurse service. Your viral load goes down when you include spirituality in your fight against HIV because your levels of cortisol — a stress hormone — go down first. "Science doesn't deal in supernatural explanations," says Richard Sloan, professor of behavioral medicine at Columbia University Medical Center and author of Blind Faith: The Unholy Alliance of Religion and Medicine. "Religion and science address different concerns."

That's undeniably true — up to a point. But it's also true that our brains and bodies contain an awful lot of spiritual wiring. Even if there's a scientific explanation for every strand of it, that doesn't mean we can't put it to powerful use. And if one of those uses can make us well, shouldn't we take advantage of it? "A large body of science shows a positive impact of religion on health," says Dr. Andrew Newberg, a professor of radiology, psychology and religious studies at the University of Pennsylvania and co-founder of Penn's Center for Spirituality and the Mind. "The way the brain works is so compatible with religion and spirituality that we're going to be enmeshed in both for a long time."

It's All in Your Head
"enmeshed in the brain" is as good a way as any to describe Newberg's work of the past 15 years. The author of four books, including the soon-to-be-released How God Changes Your Brain, he has looked more closely than most at how our spiritual data-processing center works, conducting various types of brain scans on more than 100 people, all of them in different kinds of worshipful or contemplative states. Over time, Newberg and his team have come to recognize just which parts of the brain light up during just which experiences.

When people engage in prayer, it's the frontal lobes that take the lead, since they govern focus and concentration. During very deep prayer, the parietal lobe powers down, which is what allows us to experience that sense of having loosed our earthly moorings. The frontal lobes go quieter when worshippers are involved in the singular activity of speaking in tongues — which jibes nicely with the speakers' subjective experience that they are not in control of what they're saying.

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Friday, January 02, 2009

Spirituality spot found in brain

2008-12-25 10:28

What makes us feel spiritual? It could be the quieting of a small area in our brains, a new study suggests.

The area in question - the right parietal lobe - is responsible for defining "Me," said researcher Brick Johnstone of Missouri University. It generates self-criticism, he said, and guides us through physical and social terrains by constantly updating our self-knowledge: my hand, my cocktail, my witty conversation skills, my new love interest ...

People with less active Me-Definers are more likely to lead spiritual lives, reports the study in the current issue of the journal Zygon.

Most previous research on neuro-spirituality has been based on brain scans of actively practicing adherents (i.e. meditating monks, praying nuns) and has resulted in broad and inconclusive findings. (Is the brain area lighting up in response to verse or spiritual experience?)

So Johnstone and colleague Bret Glass turned to the tried-and-true techniques of neuroscience's early days - studying brain-injured patients. The researchers tested brain regions implicated in the previous imaging studies with exams tailored to each area's expertise - similar to studying the prowess of an ear with a hearing test. They then looked for correlations between brain region performance and the subjects' self-reported spirituality.

Among the more spiritual of the 26 subjects, the researchers pinpointed a less functional right parietal lobe, a physical state which may translate psychologically as decreased self-awareness and self-focus.

The finding suggests that one core tenant of spiritual experience is selflessness, said Johnstone, adding that he hopes the study "will help people think about spirituality in more specific ways."

Spiritual outlooks have long been associated with better mental and physical health. These benefits, Johnstone speculated, may stem from being focused less on one's self and more on others - a natural consequence of turning down the volume on the Me-Definer.

In addition to religious practices, other behaviors and experiences are known to hush the Definer of Me. Appreciation of art or nature can quiet it, Johnstone said, pointing out that people talk of "losing themselves" in a particularly beautiful song. Love, and even charity work, can also soften the boundaries of "Me," he said.

The greatest silencing of the Me-Definer likely happens in the deepest states of meditation or prayer, said Johnstone, when practitioners describe feeling seamless with the entire universe. That is, the highest point of spiritual experience occurs when "Me" completely loses its definition.

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Thursday, December 25, 2008

Brain Activity Altered during Religious Experience

December 24, 2008 in Mind & Brain

A study in Zygon: Journal of Religion & Science finds that religious experience is associated with decreased activity in the brain's right parietal lobe. Cynthia Graber reports

[The following is an exact transcript of this podcast.] Please click on "exteranl link to access the entire podcast.


In America there’s a feeling of Christmas. But that’s not the only winter holiday going on. Jews are lighting Hanukkah candles, Muslims recently feasted on Eid al-Adha, and pagans celebrated the solstice. So it’s a good time for researchers to consider spirituality—from a scientific point of view.

One experience central to major religions around the world is that of transcendence, the idea of almost losing a sense of self to the feeling that there’s something bigger out there. Now scientists at the University of Missouri say they’ve located that experience in our brains. All the people studied, from Buddhist monks in meditation to Francescan nuns in prayer, experience this transcendence. And they all have decreased activity in the right parietal lobe of the brain. That area has to do with senses such as orienting yourself in the space around you. The study was published in Zygon: Journal of Religion & Science.

Interestingly, people with injuries to the right parietal lobe report increased levels of spiritual experiences. The researchers are quick to say that this connection doesn’t minimize the role of religion, and that religious or spiritual experiences might decrease activity in that region and thus increase that special feeling of transcendence. Just in time for the holidays.

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Thursday, December 18, 2008

Selflessness Has Neuropsychological Connection

By: University of Missouri - Wed, 12/17/2008

All spiritual experiences are based in the brain. That statement is truer than ever before, according to a University of Missouri neuropsychologist. An MU study has data to support a neuropsychological model that proposes spiritual experiences associated with selflessness are related to decreased activity in the right parietal lobe of the brain. The study is one of the first to use individuals with traumatic brain injury to determine this connection. Researchers say the implication of this connection means people in many disciplines, including peace studies, health care or religion can learn different ways to attain selflessness, to experience transcendence, and to help themselves and others.

This study, along with other recent neuroradiological studies of Buddhist meditators and Francescan nuns, suggests that all individuals, regardless of cultural background or religion, experience the same neuropsychological functions during spiritual experiences, such as transcendence. Transcendence, feelings of universal unity and decreased sense of self, is a core tenet of all major religions. Meditation and prayer are the primary vehicles by which such spiritual transcendence is achieved.

“The brain functions in a certain way during spiritual experiences,” said Brick Johnstone, professor of health psychology in the MU School of Health Professions. “We studied people with brain injury and found that people with injuries to the right parietal lobe of the brain reported higher levels of spiritual experiences, such as transcendence.”

This link is important, Johnstone said, because it means selflessness can be learned by decreasing activity in that part of the brain. He suggests this can be done through conscious effort, such as meditation or prayer. People with these selfless spiritual experiences also are more psychologically healthy, especially if they have positive beliefs that there is a God or higher power who loves them, Johnstone said.

“This research also addresses questions regarding the impact of neurologic versus cultural factors on spiritual experience,” Johnstone said. “The ability to connect with things beyond the self, such as transcendent experiences, seems to occur for people who minimize right parietal functioning. This can be attained through cultural practices, such as intense meditation or prayer or because of a brain injury that impairs the functioning of the right parietal lobe. Either way, our study suggests that ‘selflessness’ is a neuropsychological foundation of spiritual experiences.”

The research was funded by the MU Center on Religion and the Professions. The study – “Support for a neuropsychological model of spirituality in persons with traumatic brain injury” – was published in the peer-reviewed journal Zygon.

“Our research focused on the personal experience of spiritual transcendence and does not in any way minimize the importance of religion or personal beliefs, nor does it suggest that spiritual experience are related only to neuropsychological activity in the brain,” Johnstone said. “It is important to note that individuals experience their God or higher power in many different ways, but that all people from all religions and beliefs appear to experience these connections in a similar way.”

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Wednesday, September 24, 2008

What Happens When We Die?

By M.J. STEPHEY Tue Sep 23

A fellow at New York City's Weill Cornell Medical Center, Dr. Sam Parnia is one of the world's leading experts on the scientific study of death. Last week Parnia and his colleagues at the Human Consciousness Project announced their first major undertaking: a 3-year exploration of the biology behind "out-of-body" experiences. The study, known as AWARE (AWAreness during REsuscitation), involves the collaboration of 25 major medical centers through Europe, Canada and the U.S. and will examine some 1,500 survivors of cardiac arrest. TIME spoke with Parnia about the project's origins, its skeptics and the difference between the mind and the brain.

What sort of methods will this project use to try and verify people's claims of "near-death" experience?


When your heart stops beating, there is no blood getting to your brain. And so what happens is that within about 10 sec., brain activity ceases - as you would imagine. Yet paradoxically, 10% or 20% of people who are then brought back to life from that period, which may be a few minutes or over an hour, will report having consciousness. So the key thing here is, Are these real, or is it some sort of illusion? So the only way to tell is to have pictures only visible from the ceiling and nowhere else, because they claim they can see everything from the ceiling. So if we then get a series of 200 or 300 people who all were clinically dead, and yet they're able to come back and tell us what we were doing and were able see those pictures, that confirms consciousness really was continuing even though the brain wasn't functioning.

How does this project relate to society's perception of death?


People commonly perceive death as being a moment - you're either dead or you're alive. And that's a social definition we have. But the clinical definition we use is when the heart stops beating, the lungs stop working, and as a consequence the brain itself stops working. When doctors shine a light into someone's pupil, it's to demonstrate that there is no reflex present. The eye reflex is mediated by the brain stem, and that's the area that keeps us alive; if that doesn't work, then that means that the brain itself isn't working. At that point, I'll call a nurse into the room so I can certify that this patient is dead. Fifty years ago, people couldn't survive after that.

How is technology challenging the perception that death is a moment?

Nowadays, we have technology that's improved so that we can bring people back to life. In fact, there are drugs being developed right now - who knows if they'll ever make it to the market - that may actually slow down the process of brain-cell injury and death. Imagine you fast-forward to 10 years down the line; and you've given a patient, whose heart has just stopped, this amazing drug; and actually what it does is, it slows everything down so that the things that would've happened over an hour, now happen over two days. As medicine progresses, we will end up with lots and lots of ethical questions.

But what is happening to the individual at that time? What's really going on? Because there is a lack of blood flow, the cells go into a kind of a frenzy to keep themselves alive. And within about 5 min. or so they start to damage or change. After an hour or so the damage is so great that even if we restart the heart again and pump blood, the person can no longer be viable, because the cells have just been changed too much. And then the cells continue to change so that within a couple of days the body actually decomposes. So it's not a moment; it's a process that actually begins when the heart stops and culminates in the complete loss of the body, the decompositions of all the cells. However, ultimately what matters is, What's going on to a person's mind? What happens to the human mind and consciousness during death? Does that cease immediately as soon as the heart stops? Does it cease activity within the first 2 sec., the first 2 min.? Because we know that cells are continuously changing at that time. Does it stop after 10 min., after half an hour, after an hour? And at this point we don't know.

What was your first interview like with someone who had reported an out-of-body experience?

Eye-opening and very humbling. Because what you see is that, first of all, they are completely genuine people who are not looking for any kind of fame or attention. In many cases they haven't even told anybody else about it because they're afraid of what people will think of them. I have about 500 or so cases of people that I've interviewed since I first started out more than 10 years ago. It's the consistency of the experiences, the reality of what they were describing. I managed to speak to doctors and nurses who had been present who said these patients had told them exactly what had happened, and they couldn't explain it. I actually documented a few of those in my book What Happens When We Die because I wanted people to get both angles - not just the patients' side but also the doctors' side - and see how it feels for the doctors to have a patient come back and tell them what was going on. There was a cardiologist that I spoke with who said he hasn't told anyone else about it because he has no explanation for how this patient could have been able to describe in detail what he had said and done. He was so freaked out by it that he just decided not to think about it anymore.

Why do you think there is such resistance to studies like yours?


Because we're pushing through the boundaries of science, working against assumptions and perceptions that have been fixed. A lot of people hold this idea that, well, when you die, you die; that's it. Death is a moment - you know you're either dead or alive. All these things are not scientifically valid, but they're social perceptions. If you look back at the end of the 19th century, physicists at that time had been working with Newtonian laws of motion, and they really felt they had all the answers to everything that was out there in the universe. When we look at the world around us, Newtonian physics is perfectly sufficient. It explains most things that we deal with. But then it was discovered that actually when you look at motion at really small levels - beyond the level of the atoms - Newton's laws no longer apply. A new physics was needed, hence, we eventually ended up with quantum physics. It caused a lot of controversy - even Einstein himself didn't believe in it.

Now, if you look at the mind, consciousness, and the brain, the assumption that the mind and brain are the same thing is fine for most circumstances, because in 99% of circumstances we can't separate the mind and brain; they work at the exactly the same time. But then there are certain extreme examples, like when the brain shuts down, that we see that this assumption may no longer seem to hold true. So a new science is needed in the same way that we had to have a new quantum physics. The CERN particle accelerator may take us back to our roots. It may take us back to the first moments after the Big Bang, the very beginning. With our study, for the first time, we have the technology and the means to be able to investigate this. To see what happens at the end for us. Does something continue?

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Monday, April 21, 2008

Discovery of the God Module Results in New Field of Science: Neurotheology

Saturday, April 19, 2008
by: Barbara L. Minton

(NaturalNews) During the concentration of prayer, the encompassing peace as we draw near death, a mystical revelation, or the sense that God is talking to us, we experience the most intense experiences of our lives. Since the beginning of time, people have imbued such experiences with religious significance. But in recent years, scientists have begun to explore this spiritual realm, asking their own questions about what goes on in our brains during these extraordinary events. They have been coming up with some fascinating answers that have given birth to a new field of brain science: neurotheology, the cognitive neuroscience of religious experience and spirituality.

Early Studies and Results

In a vanguard experiment on the physical sources of spiritual consciousness, Michael Persinger, Ph.D., professor of neuroscience and psychology at Laurentian University in Canada, isolated an area of neurons in the brain's temporal lobes that repeatedly fire bursts of electrical activity when one contemplates God or has feelings of spirituality. Attempting to try to stimulate these bursts, Persinger isolated an area near the front of these temporal lobes, the amygdala, an almond shaped organ that infuses events with intense emotion and a sense of meaningfulness.

He then passed a controlled electrical current through coils on the head of his 80 subjects, creating a magnetic field that mimicked the firing patterns of the neurons in the temporal lobes. This resulted in an induced spiritual experience. The subjects reported an "opiate-like effect with a substantial decrease in anxiety, a heightened sense of well-being" that gave them the sense of not being alone. This sense was described by some as a religious experience.

At the same time While Persinger conducted his experiments, Vilayanur Ramachandran, Ph.D., director of the Brain and Perception Laboratory at the University of California at San Diego, also tuned in to the cosmic consciousness. He announced that he had discovered the 'God Module' in the brain which could be responsible for man's evolutionary instinct to believe in religion.

Ramachandran and his team studied the brains of people with an unusual type of epilepsy that affects the brain's temporal lobes. The study compared epileptic patients with normal people and a group who said they were intensely religious. Electrical monitors on their skin, a standard test of activity in the brain's temporal lobes, showed that the epileptics and the deeply religious displayed a similar response when shown words invoking spiritual belief.

According to the Ramachandran led research team, the most intriguing explanation is that the seizures cause an over-stimulation of the nerves in a part of the brain dubbed the God module. "There may be dedicated neural machinery in the temporal lobes concerned with religion. This may have evolved to impose order and stability on society." The results indicate that whether a person believes in a religion or even in God may depend on how enhanced is this part of the brain's electrical circuitry.

The idea of a single God module is regarded by most scientists, including Ramachandran, as too simplistic. A Canadian researcher, Mario Beauregard, and his student used a technique called functional magnetic resonance imaging (fMRI) to study the brain activity of Carmelite nuns while they were reliving the experience of unio mystica, an intense sensation in which they report feeling the presence of God.

With fMRI imaging, changes in blood flow in the brain may be monitored in almost real time. This allows researchers to see which regions of the brain become more or less active in different conditions. Beauregard observed that the nuns' ecstatic state was associated with a distinct pattern of activity in several areas of the brain. The researchers concluded that "mystical experiences are mediated by several brain regions and systems".

Other researchers have probed the experiences of people with temporal lobe epilepsy with interesting results. In Switzerland, Olaf Blanke and his colleagues found that electric stimulation of specific brain regions can trigger repeated out-of-body experiences. Although these experiences are somewhat common, they were not rigorously studied until Blanke came upon a case of a woman he was treating for epilepsy.

A part of the woman's brain near the junction point of the temporal and parietal lobes was stimulated with an electrode, producing the experience. Every time that part of her brain was stimulated, she described the experience as floating above her own body and watching herself.

Brain Mechanisms and Religious Experience

Shahar Arzy, a colleague of Blanke's, purposed that the junction between the temporal and parietal lobes may have played a part in some of the pivotal events in world religions. As Arzy and co-authors pointed out, many of the world's religions feature revelation experiences that take place on mountains. Many non-religious, non-mystic mountaineers have also had similar experiences while in the mountains. Time spent at high altitudes may affect the brain, according to Arzy, and "facilitate the experience of a revelation".

Arzy suggests mechanisms that could be involved in this experience. High altitudes have a significantly reduced level of oxygen which can affect the temporo-parietal junction. Stays at high altitude, particularly in solitude, might lead to low resistance to stress and loss of inhibition.

History is full of charismatic religious figures. Could any of them have been epileptics? Were the visions of Bible characters like Moses or Saint Paul reflective of temporal lobe epilepsy? There is no way to know.

Researchers suggest that these issues may have played a part in one of the mystical phenomena of ancient times, the oracle of Delphi. George Papatheodorou, an emeritus professor of geology at Patras University, and his colleagues examined the narrow cave where the Delphic priestesses were believed to have delivered their messages. They found high levels of methane, ethanol and carbon dioxide in the cave's air. "The site lies on a fault where gases leak out. These gases cause an oxygen reduction that induces a mild hypnotic state that could well produce hallucinations," he told the Greek Kathimerini newspaper.

Brain Mechanisms and Near-Death Experiences

Neurophysiologist Kevin Nelson, a researcher at the University of Kentucky in Lexington, is exploring the powerful spiritual phenomena of the near-death experience. His results have led him to believe that these experiences may be dream-like states triggered by stress and a common sleep disorder known as sleep paralysis. When people with this condition begin to awake, part of their brain stays in the random eye movement (REM) phase of sleep. They experience inability to move, resulting in frightening hallucinations.

Nelson studied 55 people who experienced near-death phenomena in a range of circumstances, including heart attacks, traffic accidents, and fainting spells. He found that about 60 percent of them reported symptoms of sleep paralysis. In a matched group of 55 healthy volunteers with no near-death experiences, only 24 percent had symptoms of sleep paralysis. Nelson concluded that his findings "anticipate that under circumstances of peril, a near-death experience is more likely in those with previous REM intrusion".

Possible Conclusions

According to the Ramachandran team, it is not clear why such dedicated neural machinery for religion may have evolved. One possibility they saw was the encouragement of tribal loyalty or reinforcement of kinship ties and the stability of closely knit clans. These scientists emphasized that their findings in no way suggest that religion is simply a matter of brain chemistry. "These studies do not in any way negate the validity of the religious experience of God," the team cautioned. "They merely provide an explanation in terms of brain regions that may be involved."


As Ramachandran has said, "We are only starting to look at this. The exciting thing is that you can even begin to contemplate scientific experiments on the neural basis of religion and God."

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Monday, March 24, 2008

Brains Are Hardwired To Act According To The Golden Rule

ScienceDaily (Mar. 23, 2008)

— Wesley Autrey, a black construction worker, a Navy veteran and 55-year-old father of two, didn’t know the young man standing beside him. But when he had a seizure on the subway platform and toppled onto the tracks, Autrey jumped down after him and shielded him with his body as a train bore down on them. Autrey could have died, so why did he put his life on the line — literally — to save this complete stranger?

Donald Pfaff, the author of the new book The Neuroscience of Fair Play: Why We (Usually) Follow the Golden Rule, thinks he has the answer. Our brains, he says, are hardwired to do unto others as we would have them do unto us. Individual acts of aggression and evil occur when this circuitry jams.

“If it’s really true that all religions have this ethical principle, across continents and across centuries, then it is more likely to have a hardwired scientific basis than if it was just a neighborhood custom,” says Pfaff, whose laboratory at Rockefeller University studies various hormones and brain signals that influence positive social behavior.

In his book, Pfaff proposes a theory that explains, in a parsimonious way, how people manage to behave well when they do, and under what conditions they deviate from good behavior. He describes how memories of fear, as well as various brain hormones, can play a vital role in whether people choose to act ethically or violently toward others. One’s behavior is a balance, he says, between “prosocial” and “antisocial” traits — a balance shaped by early life experiences.

“You have some people who are prosocial, who face the world with a smile and are uniformly nice to other people,” says Pfaff. “Others face the world with a snarl and are routinely aggressive and thoughtless. Most of us are a balance — we are able to treat each other almost all the time in a civil and thoughtful way.” But nobody’s perfect, he adds. “Even those in the prosocial group have cheated on their taxes.”

Donald W. Pfaff, Ph.D., is professor and head of the Laboratory of Neurobiology and Behavior at The Rockefeller University, a member of the National Academy of Sciences and a fellow of the American Academy of Arts and Sciences. At Rockefeller, where he has studied the brain and behavior for more than 30 years, he discovered the brain-cell targets for steroid hormones and proved that these chemicals, among others, could elicit specific behaviors when reaching the right brain areas.

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Friday, August 10, 2007

New field of neurotheology opens door for scientific study of belief

By Hannah Elliott
Published August 8, 2007


NEW YORK (ABP) -- If scientists could chart physical changes that happen in the brain during prayer, would it mean that prayer is something that happens only in the mind? And if brain scans show unique molecular activity during meditation, does that mean all religious belief is imaginary?

Scientists -- and some theologians -- are studying those questions using neurotheology, an emerging discipline that addresses the correlation between neurological and spiritual activity.

Some say neurotheology proves that God created the brain. Others believe "the brain created the god." At the root of the debate, some say, is the threat that faith could be reduced to nothing more than chemical reactions in the brain.

The coupling of science and belief has become increasingly prominent in popular media. Time and Newsweek magazines have both recently run long stories exploring the newly recognized discipline. And current studies at Wheaton College, Columbia University and the University of Pennsylvania are using neuroimaging to locate brain regions activated during emotional or spiritual events.

The quest is to find a neurological basis for out-of-body or enlightenment experiences, including trances, time perception, oneness with the universe and altered states of consciousness. But neurotheology can also help explain the more mundane habits of a religious life: prayer, beliefs, meditation and senses of the presence of the supernatural.

Paul Simmons, a clinical professor of family and community medicine at the University of Louisville School of Medicine, said the brain is intimately related to relationships with and perceptions of God -- so neurotheology is a good way to help theologians use all of their capacities to study God. The underlying question, the former pastor and ethics professor at the Southern Baptist Theological Seminary said, is whether that experience is "just a mental state or have you gotten in touch with a transcendence?"

"Our brain is basic to all that we are, all that we understand, all that we perceive," Simmons said. "We can't avoid that in theology any longer. At least, we must be aware of the fact that many of our claims made about religion are actually based on science."

Theories about correlations between the brain and beliefs are nothing new. Historians have speculated that figures like Joan of Arc, Saint Teresa of Avila, Fedor Dostoevsky and Marcel Proust had aliments like epilepsy, which in turn led to their obsessions with the spiritual world.

Modern scientists differentiate between the brain and mind by defining the brain as physical and chemical, while the mind has to do with thoughts and ideas.

Plato's ideas focused on both the brain and the mind. Aristotle argued that God is pure mind, and since people have a brain they can think "God thoughts," Simmons said. "Aristotle thought you could think pure thoughts and thus get right in touch with God."

Beginning in the 1950s, scientists used electroencephalograms, or EEGs, to record electrical activity in the brain. By placing electrodes on the scalp, they could study brain waves concurring with elevated states of consciousness. In the 1980s, they stimulated different areas of the brain with a magnetic field, causing subjects to claim senses of ethereal presences in the room.

The first modern book published on the subject came in 1994. Called Neurotheology: Virtual Religion in the 21st Century, it was promoted in a theological journal called Zygon. And Newsweek recently citied a 1998 book -- published by MIT Press, no less -- called Zen and the Brain. Since then, scholarly journals have devoted issues to religion and the mind, including studies using data from meditating Buddhist monks and praying Franciscan nuns.

The reason for the renewed interest, according to neurotheology pioneer Brian Alston, is that the people writing about it have changed the terms of the field. This popular type of neurotheology focuses on beliefs, he said.

Studies since the 1960s have consistently reported that between 30 percent and 40 percent of people have felt "very close to a powerful, spiritual force that seemed to lift you out of yourself," Newsweek reported. According to the Gallup Poll, 53 percent of Americans say they have experienced a "sudden religious awakening or insight" at least once.

But has the fascination with the brain and belief come from an oversimplified version of neurotheology? Some have criticized Time's article as equating science with Darwinism and religion with God -- over-generalized definitions for such complex subjects.

"It's oversimplified, but at the same time, there's a large kernel of truth in there," Simmons said. "The issue is whether a religious experience is a matter of brain circuits or God. Religiously inclined people will say, 'Well, that's God using our brain manifesting [itself] in brain activity.'"

Alston, who wrote What is Neurotheology?, said popular writing has certainly oversimplified the dialogue between science and theology. Theology does not just deal with the religious and the spiritual -- it has much broader implications, he said.

The word "neurobelief" -- instead of "neurotheology" -- is a better way to characterize the discipline, Alston said. Neurotheology should represent beliefs that are broader than just religious and spiritual, he added. It should represent beliefs that are cultural and political as well.

"What neurotheology tries to do is say, 'Look, here are ways that all this works together. Instead of seeing these things as enemies, let's look at these as things that can relate,'" he said. Part of the issue, he said, is that, "in the Western world, we have created a dichotomy between what we consider to be physical and what we consider to be spiritual."

That divide has been implicated in some of the criticisms of neurotheology. The key problem with neurotheology is its attempt to unify two strikingly different perspectives on human beings within one discipline, Alston wrote in a paper presented at the annual convention of the American Psychological Association last year.

Some critics believe that even if neuroscience and theology are brought together within the discipline of neurotheology, the differences will inevitably lead to one discipline -- namely theology -- dominating the other, Alston wrote.

David Wulf, a psychologist at Wheaton College in Massachusetts, has written that religious experience is actually normal brain functions happening under duress -- not communication with God.

Another prominent thinker, Massimo Pigliucci, a professor of ecology and evolution at the State University of New York at Stony Brook, has published essays questioning the discipline itself. In an essay titled "Neurotheology: A Rather Skeptical Perspective," Pigliucci wrote that he had two problems with neurotheology: "First, it is no theology at all. Theology is the study of the attributes of God.... [T]he neurological study of what happens to the brain during mystical experiences cannot tell us anything about God because all we can do is to measure neural patterns...."

The other problem, Pigliucci wrote, is that it violates Occam's razor, the rule of logic that what "can be done with fewer...is done in vain with more. That is, when faced with multiple hypotheses capable of explaining a given set of data, it is wise to start by considering the simplest ones, those that make the least unnecessary assumptions."

That logic would leave God out of the equation.

For scientists to conclude that "the self and the world at large are in fact contained within and possibly created by the reality of [an] Absolute Unitary Being" leaves the "boundaries of both science and philosophy to plunge into pure metaphysical speculation," Pigliucci wrote.

If "we realize that mystical experiences originate from the same neurological mechanisms that underlie hallucinations ... I bet dollar to donut that the reality experienced by meditating Buddhists and praying nuns is entirely contained in their mind and is not a glimpse of a 'higher' realm, as tantalizing as that idea may be," he concluded.

Simmons called that criticism "on target." Neurotheology doesn't deal with theology as it is traditionally done -- trying to get religion and experience together with reasonable consistency, he said. Progress in the field will come mostly in mental health, he said.

Alston, who studied ethics and philosophy at Yale Divinity School, says criticism of neurotheology depends on who is receiving the information. Much of it has to do with the difference between the physical brain and the metaphysical mind. Some experts believe that ideas in the mind cause action, while others say chemicals in the brain cause action -- and if chemicals are altered in the brain, behaviors will change, Alston said.

Either way of thinking is okay, since neurotheologists aren't interested in changing firmly held beliefs, he said.

"What I'm trying to do with neurotheology is to explain that each of these has a way with relating to the subject matter," he said. "It once again depends on the standing point of a person in terms of if they're a biologist and what their tools are and if they are a psychologist and what their tools are."

And with the stakes so high in this new and complex discipline, there's likely to be no shortage of opinions from either camp.

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Friday, July 13, 2007

The Early Science of Altruism

By Brandon Keim
July 12, 2007

Treat others as you'd like to be treated: that's the Golden Rule, present in some variation in just about every major culture and religion -- and, perhaps, coded into the structure of our brains.

The biological aspects of altruism are a new and exciting field of scientific research. Perhaps the insights gained in these early days will someday help us understand our own virtues and vices, and illuminate some way of nourishing a healthier, happier society -- or, from another perspective, a healthier, happier superorganism.

That, at least, is the hope -- and Jordan Grafman, chief of cognitive neuroscience at the National Institute of Neurological Disorders and Stroke, was kind enough to talk with me about research into human altruism and what it all might mean for our future....

Traditionally, with language, object, and face recognition, we know a fair amount about those. But it’s more challenging and difficult to investigate altruism or attitudes or moral cognition.... But scientists have pressed forwards, and it’s a burgeoning literature now.

On animal studies into altruism, Grafman cautions that they involve behaviors more limited than our own: when animals help each other out -- when, for example, one bird combs another for parasites -- the reward, such as a reciprocated grooming, is almost immediate. Altruism in humans is more far-sighted, and may not involve any reward at all.

Studies have shown that altruistic behavior activates the pleasure centers that reward our most basic, immediate urges for food and sex -- something that has helped to preserve these tendencies, said Grafman, but not enough to explain the complexities of our selflessness.

It feels good, for lack of a better way to say it, so you’re more likely to do that again. But that isn’t selective *for* altruistic behavior. It gets fired off in response to lots of activities.... It's not unique to altruism. There must be other brain areas that the system partners with, leading to human behaviors in particular.

That’s likely to be an area in the prefrontal cortex. Certainly in the frontal lobes we seem to have structures activated when people feel more bonding to another person or entity. That area is also activated during altruistic behavior.... That area is very important for altruistic behavior, particularly when you have to overcome constraint -- for example, you want to give, but it’s going to cost you something. The anteriopolar prefrontal cortex is one of the most evolved areas of the brain, and it’s just a very very important part for overcoming primitive responses -- [i.e.,] I’m going to do something for that person and get something immediately back....

No animal gives to an institution, whereas we’re willing to donate to United Way, which will distribute money in the future, in a way you’re not aware, to other entities, and you won’t get anything directly back.... So that, in some sense, is an internalized agreement. You give, and you'll be rewarded because you have a belief system that says it’s good. That’s human. That is human.

There’s another approach that has forced this into the open: neuroeconomic research. It's an area that’s taken classic economic experiments and put people in a brain scanner while doing these kinds of tasks. It's pushing this whole literature about higher-level human behavior. Much of economics is concerned with human economic behaviors in societies -- that's a social behavior.... Another component to this is evolutionary psychology, biology. It’s a good thing, but challenging and frightening -- the more we make this mundane, it takes the magical aspects out of that, in terms of why people give.... It’s big for day to day life.

A lot of our mores -- from religions, for example, ethics, principles -- were first put into the bibles of different religions: the Koran, New Testament, a variety of other documents serve as foundations for religious, general cultural practices. Many ethical principles, people believe to some degree, were handed down by higher authority; if that’s the case, we’re making an argument, that the brain developing in such a way that it enacts these behaviors partly because of the way that the biology of the brain is designed. It forces people to think about the issue in a more experimental way -- a testable way, rather than a more mystical one. And a lot of people live lives based on mystical ideas.

This will cause people to debate and think, and that’s good. We’ve always done that, without biology, as new ideas come. Now biology is going to put in its two cents. That alone makes it provocative. Then there are other issues that come up. In a sense, also provocative: the more we know, the more we can record information related to these kinds of behaviors, the better we can assess or predict them in others, without people telling us what they're going to do.

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Thursday, May 24, 2007

Spirit Tech

How to wire your brain for religious ecstasy.
By John Horgan

Posted Thursday, April 26, 2007, at 7:19 AM ET


Eight years ago, I flew to Laurentian University in Midwestern Canada to test a gadget that some journalists called the "God machine." The device consisted of computer-controlled solenoids that fit over the skull and stimulate the brain with electromagnetic pulses. Its inventor, neuroscientist Michael Persinger, claimed that it could induce mystical experiences, including, as Wired magazine put it, visions of "Jesus, the Virgin Mary, Mohammed, the Sky Spirit."

Persinger is one of the more colorful characters in the fast-growing, flakey field of neurotheology, which studies what is arguably the most complex manifestation—spirituality—of the most complex phenomenon—the human brain—known to science. Given that brain researchers have no idea how I conceived and typed this sentence, I doubt they will ever account for religious experiences in all their vast diversity and subtlety. Nor will they solve the riddle of whether God actually exists or is a figment of our evolved imaginations, like unicorns or superstrings. Neurotheology may nonetheless have a profound social impact, by yielding more potent, reliable methods of inducing spiritual experiences.

Surveys suggest that only about one in three people has ever had a mystical experience, defined by one poll as the sensation of "a powerful spiritual force that seemed to lift you out of yourself."

Humans have long sought such experiences through meditation, yoga, prayer, guru-worship, fasting, and flagellation, but these methods are unreliable, notes James Austin, author of Zen and the Brain, one of the best books on neurotheology. Austin hopes that neurotheology will eventually yield much more potent, precise methods of inducing transcendent experiences, from fleeting feelings of connectedness all the way up to "the full moon of enlightenment."

Persinger's God machine may not have done much for me, but here's a brief status report on four mystical technologies with potential:

Mystical Brain Chips

In the 1950s, Canadian neurosurgeon Wilder Penfield, while preparing epileptic patients for surgery, stimulated their exposed brains with electrodes. Some patients heard voices or music and saw apparitions when their temporal lobes were stimulated. Upon learning about Penfield's experiments, Aldous Huxley wrote: "Is there, one wonders, some area in the brain from which the probing electrode could elicit Blake's Cherubim?"

One still wonders. A Swiss team recently induced out-of-body experiences in an epileptic patient about to undergo surgery by stimulating her right angular gyrus, which underpins spatial awareness. Other groups have shown that implanted electrodes can trigger euphoria, and in fact they are now being tested as treatments for severe depression (as well as paralysis, tremors, and epilepsy). In principle, implants would provide the most precise, powerful means of inducing religious ecstasy. Indeed, self-described "Wireheads" look forward to the day when these devices will vanquish mental suffering and deliver ecstasy on demand. But for now, this technology—which requires inserting wires into the brain through holes drilled in the skull—remains too risky for all but the most desperate patients.

Magic Wands

Transcranial magnetic stimulation, or TMS, is noninvasive and hence safer and easier to test than implants. Researchers have reported success in treating depression and other disorders with this method, which often employs electromagnetic "wands" as well as headsets. Persinger insists that TMS, properly used, can also induce intense mystical experiences.

A group at Uppsala University has tried and failed to replicate Persinger's results in a controlled, double-blind experiment. Todd Murphy, a neuroscientist who has worked with Persinger, is nonetheless marketing a version of the God machine called the "Shakti" (a Hindu term for divinity), which according to Murphy's Web site "uses magnetic fields to create altered states."

Tweaking the God Gene

The work of Dean Hamer, a geneticist at the National Cancer Institute, raises the prospect of genetically engineered mystics. Hamer claims to have found a gene associated with "self-transcendence" or "spirituality" in a group of 1,000 subjects who filled out surveys that probed their beliefs in God, ESP, and so on. Hamer calls this gene "the spiritual allele" or, even more dramatically, the "God gene"—which is also the title of the popular book in which he describes his research. Francis Collins, director of the Human Genome Project, has called Hamer's claim "wildly overstated."

Rick Strassman, a psychiatrist at the University of New Mexico, suggests focusing on genes associated with dimethyltryptamine, the only psychedelic known to occur naturally in the human brain. In his book DMT: The Spirit Molecule, Strassman presents evidence that endogenous DMT underpins mystical visions, psychotic hallucinations, alien-abduction experiences, near-death experiences, and other exotic cognitive phenomena.

Our natural mystical capacity, Strassman speculates, might be enhanced with genetic modifications that boost the production of DMT or of the enzymes that catalyze its effects. A clever, unscrupulous geneticist might even transform us all into mystics without our consent. "I can envision a situation where a cold virus is tinkered with to turn on our methylating enzymes," Strassman says, "spreads around the world in a couple of years, and there you have it."

Good Old Psychedelics

Psychedelic (or entheogenic, literally God-containing) compounds such as LSD and psilocybin represent by far the most mature mystical technology available. Legal research into the therapeutic and spiritual benefits of psychedelics collapsed in the late 1960s after the drugs were outlawed but is now undergoing a renaissance.

Reseachers at UCLA, the University of Arizona, Harvard, and other institutions are treating post-traumatic stress disorder, obsessive-compulsive disorder, and anxiety with psilocybin and MDMA (aka Ecstasy). Last year, a team at Johns Hopkins University reported that psilocybin had triggered profound spiritual experiences in two-thirds of a group of 36 subjects. "Psilocybin, the active ingredient of 'magic mushrooms,' expands the mind," the Washington Post noted drily. "After a thousand years of use, that's now scientifically official."

Independent chemist Alexander Shulgin has identified more than 200 psychotropic compounds that have potential as therapeutic and spiritual catalysts.

Our current mystical technologies are primitive, but one day, neurotheologians may find a technology that gives us permanent, blissful self-transcendence with no side effects. Should we really welcome such a development? Recall that in the 1950s and 1960s, the CIA funded research on psychedelics because of their potential as brainwashing agents and truth serums.

Even setting aside the issue of control, mystical technologies raise troubling philosophical issues. Shulgin, the psychedelic chemist, once wrote that a perfect mystical technology would bring about "the ultimate evolution, and perhaps the end of the human experiment." When I asked Shulgin to elaborate, he said that if we achieve permanent mystical bliss, there would be "no motivation, no urge to change anything, no creativity." Both science and religion aim to eliminate suffering. But if a mystical technology makes us immune to anxiety, grief, and heartache, are we still fully human? Have we gained something or lost something? In short, would a truly effective mystical technology—a God machine that works—save us, or doom us?

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