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TruthBook Religious News Blog



Monday, April 21, 2008

Discovery of the God Module Results in New Field of Science: Neurotheology

Saturday, April 19, 2008
by: Barbara L. Minton

(NaturalNews) During the concentration of prayer, the encompassing peace as we draw near death, a mystical revelation, or the sense that God is talking to us, we experience the most intense experiences of our lives. Since the beginning of time, people have imbued such experiences with religious significance. But in recent years, scientists have begun to explore this spiritual realm, asking their own questions about what goes on in our brains during these extraordinary events. They have been coming up with some fascinating answers that have given birth to a new field of brain science: neurotheology, the cognitive neuroscience of religious experience and spirituality.

Early Studies and Results

In a vanguard experiment on the physical sources of spiritual consciousness, Michael Persinger, Ph.D., professor of neuroscience and psychology at Laurentian University in Canada, isolated an area of neurons in the brain's temporal lobes that repeatedly fire bursts of electrical activity when one contemplates God or has feelings of spirituality. Attempting to try to stimulate these bursts, Persinger isolated an area near the front of these temporal lobes, the amygdala, an almond shaped organ that infuses events with intense emotion and a sense of meaningfulness.

He then passed a controlled electrical current through coils on the head of his 80 subjects, creating a magnetic field that mimicked the firing patterns of the neurons in the temporal lobes. This resulted in an induced spiritual experience. The subjects reported an "opiate-like effect with a substantial decrease in anxiety, a heightened sense of well-being" that gave them the sense of not being alone. This sense was described by some as a religious experience.

At the same time While Persinger conducted his experiments, Vilayanur Ramachandran, Ph.D., director of the Brain and Perception Laboratory at the University of California at San Diego, also tuned in to the cosmic consciousness. He announced that he had discovered the 'God Module' in the brain which could be responsible for man's evolutionary instinct to believe in religion.

Ramachandran and his team studied the brains of people with an unusual type of epilepsy that affects the brain's temporal lobes. The study compared epileptic patients with normal people and a group who said they were intensely religious. Electrical monitors on their skin, a standard test of activity in the brain's temporal lobes, showed that the epileptics and the deeply religious displayed a similar response when shown words invoking spiritual belief.

According to the Ramachandran led research team, the most intriguing explanation is that the seizures cause an over-stimulation of the nerves in a part of the brain dubbed the God module. "There may be dedicated neural machinery in the temporal lobes concerned with religion. This may have evolved to impose order and stability on society." The results indicate that whether a person believes in a religion or even in God may depend on how enhanced is this part of the brain's electrical circuitry.

The idea of a single God module is regarded by most scientists, including Ramachandran, as too simplistic. A Canadian researcher, Mario Beauregard, and his student used a technique called functional magnetic resonance imaging (fMRI) to study the brain activity of Carmelite nuns while they were reliving the experience of unio mystica, an intense sensation in which they report feeling the presence of God.

With fMRI imaging, changes in blood flow in the brain may be monitored in almost real time. This allows researchers to see which regions of the brain become more or less active in different conditions. Beauregard observed that the nuns' ecstatic state was associated with a distinct pattern of activity in several areas of the brain. The researchers concluded that "mystical experiences are mediated by several brain regions and systems".

Other researchers have probed the experiences of people with temporal lobe epilepsy with interesting results. In Switzerland, Olaf Blanke and his colleagues found that electric stimulation of specific brain regions can trigger repeated out-of-body experiences. Although these experiences are somewhat common, they were not rigorously studied until Blanke came upon a case of a woman he was treating for epilepsy.

A part of the woman's brain near the junction point of the temporal and parietal lobes was stimulated with an electrode, producing the experience. Every time that part of her brain was stimulated, she described the experience as floating above her own body and watching herself.

Brain Mechanisms and Religious Experience

Shahar Arzy, a colleague of Blanke's, purposed that the junction between the temporal and parietal lobes may have played a part in some of the pivotal events in world religions. As Arzy and co-authors pointed out, many of the world's religions feature revelation experiences that take place on mountains. Many non-religious, non-mystic mountaineers have also had similar experiences while in the mountains. Time spent at high altitudes may affect the brain, according to Arzy, and "facilitate the experience of a revelation".

Arzy suggests mechanisms that could be involved in this experience. High altitudes have a significantly reduced level of oxygen which can affect the temporo-parietal junction. Stays at high altitude, particularly in solitude, might lead to low resistance to stress and loss of inhibition.

History is full of charismatic religious figures. Could any of them have been epileptics? Were the visions of Bible characters like Moses or Saint Paul reflective of temporal lobe epilepsy? There is no way to know.

Researchers suggest that these issues may have played a part in one of the mystical phenomena of ancient times, the oracle of Delphi. George Papatheodorou, an emeritus professor of geology at Patras University, and his colleagues examined the narrow cave where the Delphic priestesses were believed to have delivered their messages. They found high levels of methane, ethanol and carbon dioxide in the cave's air. "The site lies on a fault where gases leak out. These gases cause an oxygen reduction that induces a mild hypnotic state that could well produce hallucinations," he told the Greek Kathimerini newspaper.

Brain Mechanisms and Near-Death Experiences

Neurophysiologist Kevin Nelson, a researcher at the University of Kentucky in Lexington, is exploring the powerful spiritual phenomena of the near-death experience. His results have led him to believe that these experiences may be dream-like states triggered by stress and a common sleep disorder known as sleep paralysis. When people with this condition begin to awake, part of their brain stays in the random eye movement (REM) phase of sleep. They experience inability to move, resulting in frightening hallucinations.

Nelson studied 55 people who experienced near-death phenomena in a range of circumstances, including heart attacks, traffic accidents, and fainting spells. He found that about 60 percent of them reported symptoms of sleep paralysis. In a matched group of 55 healthy volunteers with no near-death experiences, only 24 percent had symptoms of sleep paralysis. Nelson concluded that his findings "anticipate that under circumstances of peril, a near-death experience is more likely in those with previous REM intrusion".

Possible Conclusions

According to the Ramachandran team, it is not clear why such dedicated neural machinery for religion may have evolved. One possibility they saw was the encouragement of tribal loyalty or reinforcement of kinship ties and the stability of closely knit clans. These scientists emphasized that their findings in no way suggest that religion is simply a matter of brain chemistry. "These studies do not in any way negate the validity of the religious experience of God," the team cautioned. "They merely provide an explanation in terms of brain regions that may be involved."


As Ramachandran has said, "We are only starting to look at this. The exciting thing is that you can even begin to contemplate scientific experiments on the neural basis of religion and God."

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Monday, March 24, 2008

Brains Are Hardwired To Act According To The Golden Rule

ScienceDaily (Mar. 23, 2008)

— Wesley Autrey, a black construction worker, a Navy veteran and 55-year-old father of two, didn’t know the young man standing beside him. But when he had a seizure on the subway platform and toppled onto the tracks, Autrey jumped down after him and shielded him with his body as a train bore down on them. Autrey could have died, so why did he put his life on the line — literally — to save this complete stranger?

Donald Pfaff, the author of the new book The Neuroscience of Fair Play: Why We (Usually) Follow the Golden Rule, thinks he has the answer. Our brains, he says, are hardwired to do unto others as we would have them do unto us. Individual acts of aggression and evil occur when this circuitry jams.

“If it’s really true that all religions have this ethical principle, across continents and across centuries, then it is more likely to have a hardwired scientific basis than if it was just a neighborhood custom,” says Pfaff, whose laboratory at Rockefeller University studies various hormones and brain signals that influence positive social behavior.

In his book, Pfaff proposes a theory that explains, in a parsimonious way, how people manage to behave well when they do, and under what conditions they deviate from good behavior. He describes how memories of fear, as well as various brain hormones, can play a vital role in whether people choose to act ethically or violently toward others. One’s behavior is a balance, he says, between “prosocial” and “antisocial” traits — a balance shaped by early life experiences.

“You have some people who are prosocial, who face the world with a smile and are uniformly nice to other people,” says Pfaff. “Others face the world with a snarl and are routinely aggressive and thoughtless. Most of us are a balance — we are able to treat each other almost all the time in a civil and thoughtful way.” But nobody’s perfect, he adds. “Even those in the prosocial group have cheated on their taxes.”

Donald W. Pfaff, Ph.D., is professor and head of the Laboratory of Neurobiology and Behavior at The Rockefeller University, a member of the National Academy of Sciences and a fellow of the American Academy of Arts and Sciences. At Rockefeller, where he has studied the brain and behavior for more than 30 years, he discovered the brain-cell targets for steroid hormones and proved that these chemicals, among others, could elicit specific behaviors when reaching the right brain areas.

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Friday, August 10, 2007

New field of neurotheology opens door for scientific study of belief

By Hannah Elliott
Published August 8, 2007


NEW YORK (ABP) -- If scientists could chart physical changes that happen in the brain during prayer, would it mean that prayer is something that happens only in the mind? And if brain scans show unique molecular activity during meditation, does that mean all religious belief is imaginary?

Scientists -- and some theologians -- are studying those questions using neurotheology, an emerging discipline that addresses the correlation between neurological and spiritual activity.

Some say neurotheology proves that God created the brain. Others believe "the brain created the god." At the root of the debate, some say, is the threat that faith could be reduced to nothing more than chemical reactions in the brain.

The coupling of science and belief has become increasingly prominent in popular media. Time and Newsweek magazines have both recently run long stories exploring the newly recognized discipline. And current studies at Wheaton College, Columbia University and the University of Pennsylvania are using neuroimaging to locate brain regions activated during emotional or spiritual events.

The quest is to find a neurological basis for out-of-body or enlightenment experiences, including trances, time perception, oneness with the universe and altered states of consciousness. But neurotheology can also help explain the more mundane habits of a religious life: prayer, beliefs, meditation and senses of the presence of the supernatural.

Paul Simmons, a clinical professor of family and community medicine at the University of Louisville School of Medicine, said the brain is intimately related to relationships with and perceptions of God -- so neurotheology is a good way to help theologians use all of their capacities to study God. The underlying question, the former pastor and ethics professor at the Southern Baptist Theological Seminary said, is whether that experience is "just a mental state or have you gotten in touch with a transcendence?"

"Our brain is basic to all that we are, all that we understand, all that we perceive," Simmons said. "We can't avoid that in theology any longer. At least, we must be aware of the fact that many of our claims made about religion are actually based on science."

Theories about correlations between the brain and beliefs are nothing new. Historians have speculated that figures like Joan of Arc, Saint Teresa of Avila, Fedor Dostoevsky and Marcel Proust had aliments like epilepsy, which in turn led to their obsessions with the spiritual world.

Modern scientists differentiate between the brain and mind by defining the brain as physical and chemical, while the mind has to do with thoughts and ideas.

Plato's ideas focused on both the brain and the mind. Aristotle argued that God is pure mind, and since people have a brain they can think "God thoughts," Simmons said. "Aristotle thought you could think pure thoughts and thus get right in touch with God."

Beginning in the 1950s, scientists used electroencephalograms, or EEGs, to record electrical activity in the brain. By placing electrodes on the scalp, they could study brain waves concurring with elevated states of consciousness. In the 1980s, they stimulated different areas of the brain with a magnetic field, causing subjects to claim senses of ethereal presences in the room.

The first modern book published on the subject came in 1994. Called Neurotheology: Virtual Religion in the 21st Century, it was promoted in a theological journal called Zygon. And Newsweek recently citied a 1998 book -- published by MIT Press, no less -- called Zen and the Brain. Since then, scholarly journals have devoted issues to religion and the mind, including studies using data from meditating Buddhist monks and praying Franciscan nuns.

The reason for the renewed interest, according to neurotheology pioneer Brian Alston, is that the people writing about it have changed the terms of the field. This popular type of neurotheology focuses on beliefs, he said.

Studies since the 1960s have consistently reported that between 30 percent and 40 percent of people have felt "very close to a powerful, spiritual force that seemed to lift you out of yourself," Newsweek reported. According to the Gallup Poll, 53 percent of Americans say they have experienced a "sudden religious awakening or insight" at least once.

But has the fascination with the brain and belief come from an oversimplified version of neurotheology? Some have criticized Time's article as equating science with Darwinism and religion with God -- over-generalized definitions for such complex subjects.

"It's oversimplified, but at the same time, there's a large kernel of truth in there," Simmons said. "The issue is whether a religious experience is a matter of brain circuits or God. Religiously inclined people will say, 'Well, that's God using our brain manifesting [itself] in brain activity.'"

Alston, who wrote What is Neurotheology?, said popular writing has certainly oversimplified the dialogue between science and theology. Theology does not just deal with the religious and the spiritual -- it has much broader implications, he said.

The word "neurobelief" -- instead of "neurotheology" -- is a better way to characterize the discipline, Alston said. Neurotheology should represent beliefs that are broader than just religious and spiritual, he added. It should represent beliefs that are cultural and political as well.

"What neurotheology tries to do is say, 'Look, here are ways that all this works together. Instead of seeing these things as enemies, let's look at these as things that can relate,'" he said. Part of the issue, he said, is that, "in the Western world, we have created a dichotomy between what we consider to be physical and what we consider to be spiritual."

That divide has been implicated in some of the criticisms of neurotheology. The key problem with neurotheology is its attempt to unify two strikingly different perspectives on human beings within one discipline, Alston wrote in a paper presented at the annual convention of the American Psychological Association last year.

Some critics believe that even if neuroscience and theology are brought together within the discipline of neurotheology, the differences will inevitably lead to one discipline -- namely theology -- dominating the other, Alston wrote.

David Wulf, a psychologist at Wheaton College in Massachusetts, has written that religious experience is actually normal brain functions happening under duress -- not communication with God.

Another prominent thinker, Massimo Pigliucci, a professor of ecology and evolution at the State University of New York at Stony Brook, has published essays questioning the discipline itself. In an essay titled "Neurotheology: A Rather Skeptical Perspective," Pigliucci wrote that he had two problems with neurotheology: "First, it is no theology at all. Theology is the study of the attributes of God.... [T]he neurological study of what happens to the brain during mystical experiences cannot tell us anything about God because all we can do is to measure neural patterns...."

The other problem, Pigliucci wrote, is that it violates Occam's razor, the rule of logic that what "can be done with fewer...is done in vain with more. That is, when faced with multiple hypotheses capable of explaining a given set of data, it is wise to start by considering the simplest ones, those that make the least unnecessary assumptions."

That logic would leave God out of the equation.

For scientists to conclude that "the self and the world at large are in fact contained within and possibly created by the reality of [an] Absolute Unitary Being" leaves the "boundaries of both science and philosophy to plunge into pure metaphysical speculation," Pigliucci wrote.

If "we realize that mystical experiences originate from the same neurological mechanisms that underlie hallucinations ... I bet dollar to donut that the reality experienced by meditating Buddhists and praying nuns is entirely contained in their mind and is not a glimpse of a 'higher' realm, as tantalizing as that idea may be," he concluded.

Simmons called that criticism "on target." Neurotheology doesn't deal with theology as it is traditionally done -- trying to get religion and experience together with reasonable consistency, he said. Progress in the field will come mostly in mental health, he said.

Alston, who studied ethics and philosophy at Yale Divinity School, says criticism of neurotheology depends on who is receiving the information. Much of it has to do with the difference between the physical brain and the metaphysical mind. Some experts believe that ideas in the mind cause action, while others say chemicals in the brain cause action -- and if chemicals are altered in the brain, behaviors will change, Alston said.

Either way of thinking is okay, since neurotheologists aren't interested in changing firmly held beliefs, he said.

"What I'm trying to do with neurotheology is to explain that each of these has a way with relating to the subject matter," he said. "It once again depends on the standing point of a person in terms of if they're a biologist and what their tools are and if they are a psychologist and what their tools are."

And with the stakes so high in this new and complex discipline, there's likely to be no shortage of opinions from either camp.

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Friday, July 13, 2007

The Early Science of Altruism

By Brandon Keim
July 12, 2007

Treat others as you'd like to be treated: that's the Golden Rule, present in some variation in just about every major culture and religion -- and, perhaps, coded into the structure of our brains.

The biological aspects of altruism are a new and exciting field of scientific research. Perhaps the insights gained in these early days will someday help us understand our own virtues and vices, and illuminate some way of nourishing a healthier, happier society -- or, from another perspective, a healthier, happier superorganism.

That, at least, is the hope -- and Jordan Grafman, chief of cognitive neuroscience at the National Institute of Neurological Disorders and Stroke, was kind enough to talk with me about research into human altruism and what it all might mean for our future....

Traditionally, with language, object, and face recognition, we know a fair amount about those. But it’s more challenging and difficult to investigate altruism or attitudes or moral cognition.... But scientists have pressed forwards, and it’s a burgeoning literature now.

On animal studies into altruism, Grafman cautions that they involve behaviors more limited than our own: when animals help each other out -- when, for example, one bird combs another for parasites -- the reward, such as a reciprocated grooming, is almost immediate. Altruism in humans is more far-sighted, and may not involve any reward at all.

Studies have shown that altruistic behavior activates the pleasure centers that reward our most basic, immediate urges for food and sex -- something that has helped to preserve these tendencies, said Grafman, but not enough to explain the complexities of our selflessness.

It feels good, for lack of a better way to say it, so you’re more likely to do that again. But that isn’t selective *for* altruistic behavior. It gets fired off in response to lots of activities.... It's not unique to altruism. There must be other brain areas that the system partners with, leading to human behaviors in particular.

That’s likely to be an area in the prefrontal cortex. Certainly in the frontal lobes we seem to have structures activated when people feel more bonding to another person or entity. That area is also activated during altruistic behavior.... That area is very important for altruistic behavior, particularly when you have to overcome constraint -- for example, you want to give, but it’s going to cost you something. The anteriopolar prefrontal cortex is one of the most evolved areas of the brain, and it’s just a very very important part for overcoming primitive responses -- [i.e.,] I’m going to do something for that person and get something immediately back....

No animal gives to an institution, whereas we’re willing to donate to United Way, which will distribute money in the future, in a way you’re not aware, to other entities, and you won’t get anything directly back.... So that, in some sense, is an internalized agreement. You give, and you'll be rewarded because you have a belief system that says it’s good. That’s human. That is human.

There’s another approach that has forced this into the open: neuroeconomic research. It's an area that’s taken classic economic experiments and put people in a brain scanner while doing these kinds of tasks. It's pushing this whole literature about higher-level human behavior. Much of economics is concerned with human economic behaviors in societies -- that's a social behavior.... Another component to this is evolutionary psychology, biology. It’s a good thing, but challenging and frightening -- the more we make this mundane, it takes the magical aspects out of that, in terms of why people give.... It’s big for day to day life.

A lot of our mores -- from religions, for example, ethics, principles -- were first put into the bibles of different religions: the Koran, New Testament, a variety of other documents serve as foundations for religious, general cultural practices. Many ethical principles, people believe to some degree, were handed down by higher authority; if that’s the case, we’re making an argument, that the brain developing in such a way that it enacts these behaviors partly because of the way that the biology of the brain is designed. It forces people to think about the issue in a more experimental way -- a testable way, rather than a more mystical one. And a lot of people live lives based on mystical ideas.

This will cause people to debate and think, and that’s good. We’ve always done that, without biology, as new ideas come. Now biology is going to put in its two cents. That alone makes it provocative. Then there are other issues that come up. In a sense, also provocative: the more we know, the more we can record information related to these kinds of behaviors, the better we can assess or predict them in others, without people telling us what they're going to do.

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Thursday, May 24, 2007

Spirit Tech

How to wire your brain for religious ecstasy.
By John Horgan

Posted Thursday, April 26, 2007, at 7:19 AM ET


Eight years ago, I flew to Laurentian University in Midwestern Canada to test a gadget that some journalists called the "God machine." The device consisted of computer-controlled solenoids that fit over the skull and stimulate the brain with electromagnetic pulses. Its inventor, neuroscientist Michael Persinger, claimed that it could induce mystical experiences, including, as Wired magazine put it, visions of "Jesus, the Virgin Mary, Mohammed, the Sky Spirit."

Persinger is one of the more colorful characters in the fast-growing, flakey field of neurotheology, which studies what is arguably the most complex manifestation—spirituality—of the most complex phenomenon—the human brain—known to science. Given that brain researchers have no idea how I conceived and typed this sentence, I doubt they will ever account for religious experiences in all their vast diversity and subtlety. Nor will they solve the riddle of whether God actually exists or is a figment of our evolved imaginations, like unicorns or superstrings. Neurotheology may nonetheless have a profound social impact, by yielding more potent, reliable methods of inducing spiritual experiences.

Surveys suggest that only about one in three people has ever had a mystical experience, defined by one poll as the sensation of "a powerful spiritual force that seemed to lift you out of yourself."

Humans have long sought such experiences through meditation, yoga, prayer, guru-worship, fasting, and flagellation, but these methods are unreliable, notes James Austin, author of Zen and the Brain, one of the best books on neurotheology. Austin hopes that neurotheology will eventually yield much more potent, precise methods of inducing transcendent experiences, from fleeting feelings of connectedness all the way up to "the full moon of enlightenment."

Persinger's God machine may not have done much for me, but here's a brief status report on four mystical technologies with potential:

Mystical Brain Chips

In the 1950s, Canadian neurosurgeon Wilder Penfield, while preparing epileptic patients for surgery, stimulated their exposed brains with electrodes. Some patients heard voices or music and saw apparitions when their temporal lobes were stimulated. Upon learning about Penfield's experiments, Aldous Huxley wrote: "Is there, one wonders, some area in the brain from which the probing electrode could elicit Blake's Cherubim?"

One still wonders. A Swiss team recently induced out-of-body experiences in an epileptic patient about to undergo surgery by stimulating her right angular gyrus, which underpins spatial awareness. Other groups have shown that implanted electrodes can trigger euphoria, and in fact they are now being tested as treatments for severe depression (as well as paralysis, tremors, and epilepsy). In principle, implants would provide the most precise, powerful means of inducing religious ecstasy. Indeed, self-described "Wireheads" look forward to the day when these devices will vanquish mental suffering and deliver ecstasy on demand. But for now, this technology—which requires inserting wires into the brain through holes drilled in the skull—remains too risky for all but the most desperate patients.

Magic Wands

Transcranial magnetic stimulation, or TMS, is noninvasive and hence safer and easier to test than implants. Researchers have reported success in treating depression and other disorders with this method, which often employs electromagnetic "wands" as well as headsets. Persinger insists that TMS, properly used, can also induce intense mystical experiences.

A group at Uppsala University has tried and failed to replicate Persinger's results in a controlled, double-blind experiment. Todd Murphy, a neuroscientist who has worked with Persinger, is nonetheless marketing a version of the God machine called the "Shakti" (a Hindu term for divinity), which according to Murphy's Web site "uses magnetic fields to create altered states."

Tweaking the God Gene

The work of Dean Hamer, a geneticist at the National Cancer Institute, raises the prospect of genetically engineered mystics. Hamer claims to have found a gene associated with "self-transcendence" or "spirituality" in a group of 1,000 subjects who filled out surveys that probed their beliefs in God, ESP, and so on. Hamer calls this gene "the spiritual allele" or, even more dramatically, the "God gene"—which is also the title of the popular book in which he describes his research. Francis Collins, director of the Human Genome Project, has called Hamer's claim "wildly overstated."

Rick Strassman, a psychiatrist at the University of New Mexico, suggests focusing on genes associated with dimethyltryptamine, the only psychedelic known to occur naturally in the human brain. In his book DMT: The Spirit Molecule, Strassman presents evidence that endogenous DMT underpins mystical visions, psychotic hallucinations, alien-abduction experiences, near-death experiences, and other exotic cognitive phenomena.

Our natural mystical capacity, Strassman speculates, might be enhanced with genetic modifications that boost the production of DMT or of the enzymes that catalyze its effects. A clever, unscrupulous geneticist might even transform us all into mystics without our consent. "I can envision a situation where a cold virus is tinkered with to turn on our methylating enzymes," Strassman says, "spreads around the world in a couple of years, and there you have it."

Good Old Psychedelics

Psychedelic (or entheogenic, literally God-containing) compounds such as LSD and psilocybin represent by far the most mature mystical technology available. Legal research into the therapeutic and spiritual benefits of psychedelics collapsed in the late 1960s after the drugs were outlawed but is now undergoing a renaissance.

Reseachers at UCLA, the University of Arizona, Harvard, and other institutions are treating post-traumatic stress disorder, obsessive-compulsive disorder, and anxiety with psilocybin and MDMA (aka Ecstasy). Last year, a team at Johns Hopkins University reported that psilocybin had triggered profound spiritual experiences in two-thirds of a group of 36 subjects. "Psilocybin, the active ingredient of 'magic mushrooms,' expands the mind," the Washington Post noted drily. "After a thousand years of use, that's now scientifically official."

Independent chemist Alexander Shulgin has identified more than 200 psychotropic compounds that have potential as therapeutic and spiritual catalysts.

Our current mystical technologies are primitive, but one day, neurotheologians may find a technology that gives us permanent, blissful self-transcendence with no side effects. Should we really welcome such a development? Recall that in the 1950s and 1960s, the CIA funded research on psychedelics because of their potential as brainwashing agents and truth serums.

Even setting aside the issue of control, mystical technologies raise troubling philosophical issues. Shulgin, the psychedelic chemist, once wrote that a perfect mystical technology would bring about "the ultimate evolution, and perhaps the end of the human experiment." When I asked Shulgin to elaborate, he said that if we achieve permanent mystical bliss, there would be "no motivation, no urge to change anything, no creativity." Both science and religion aim to eliminate suffering. But if a mystical technology makes us immune to anxiety, grief, and heartache, are we still fully human? Have we gained something or lost something? In short, would a truly effective mystical technology—a God machine that works—save us, or doom us?

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